562 research outputs found

    MicroRNAs in Invasion and Metastasis in Lung Cancer

    Get PDF

    Real-Time Neural Video Recovery and Enhancement on Mobile Devices

    Full text link
    As mobile devices become increasingly popular for video streaming, it's crucial to optimize the streaming experience for these devices. Although deep learning-based video enhancement techniques are gaining attention, most of them cannot support real-time enhancement on mobile devices. Additionally, many of these techniques are focused solely on super-resolution and cannot handle partial or complete loss or corruption of video frames, which is common on the Internet and wireless networks. To overcome these challenges, we present a novel approach in this paper. Our approach consists of (i) a novel video frame recovery scheme, (ii) a new super-resolution algorithm, and (iii) a receiver enhancement-aware video bit rate adaptation algorithm. We have implemented our approach on an iPhone 12, and it can support 30 frames per second (FPS). We have evaluated our approach in various networks such as WiFi, 3G, 4G, and 5G networks. Our evaluation shows that our approach enables real-time enhancement and results in a significant increase in video QoE (Quality of Experience) of 24\% - 82\% in our video streaming system

    hsa-miR-125a-5p Enhances Invasion Ability in Non-Small Lung Carcinoma Cell Lines

    Get PDF
    Background and objective MicroRNAs (miRNAs) are short non-coding RNAs that posttranscriptionally regulate gene expression by partially binding complementary to target sites in mRNAs. Although some impaired miRNA regulations have been observed in many human cancers, the functions of miR-125a are still unclear. The aim of this study is to investigate the expression of hsa-miR-125a-5p in NSCLC cell lines and the relationship between hsa-miR-125a-5p and the invasion of lung cancer cells. Methods The expression of hsa-miR-125a-5p and the effectiveness for a given period time after being transfected sense hsa-miR-125a-5p 2’-O-methyl oligonucleotide, which were 24 h, 36 h, 48 h, 60 h and 72 h, were examined by realtime PCR. Meanwhile, we investigated the modification of invasive ability in A549 and NCI-H460 cells by transwell. Results Real-time PCR showed that hsa-miR-125a-5p was poorly-expressed in 6 lung cancer cell lines, especially in LH7, NCI-H460, SPC-A-1 and A549. The highest expression of hsa-miR-125a-5p occurred in the cells transfected with sense hsa-miR-125a-5p 2’-O-methyl oligonucleotide 36 h. Furthermore, the invasive abilities of A549 and NCI-H46O were enhanced by up-regulating hsa-miR-125a-5p. Conclusion hsa-miR-125a-5p was poorly-expressed in lung cancer cells and it could enhance lung cancer cell invasion by up-regulating hsa-miR-125a-5p

    Neural Video Recovery for Cloud Gaming

    Full text link
    Cloud gaming is a multi-billion dollar industry. A client in cloud gaming sends its movement to the game server on the Internet, which renders and transmits the resulting video back. In order to provide a good gaming experience, a latency below 80 ms is required. This means that video rendering, encoding, transmission, decoding, and display have to finish within that time frame, which is especially challenging to achieve due to server overload, network congestion, and losses. In this paper, we propose a new method for recovering lost or corrupted video frames in cloud gaming. Unlike traditional video frame recovery, our approach uses game states to significantly enhance recovery accuracy and utilizes partially decoded frames to recover lost portions. We develop a holistic system that consists of (i) efficiently extracting game states, (ii) modifying H.264 video decoder to generate a mask to indicate which portions of video frames need recovery, and (iii) designing a novel neural network to recover either complete or partial video frames. Our approach is extensively evaluated using iPhone 12 and laptop implementations, and we demonstrate the utility of game states in the game video recovery and the effectiveness of our overall design

    Inspiratory-Activated Airway Vagal Preganglionic Neurones Excited by Thyrotropin-Releasing Hormone via Multiple Mechanisms in Neonatal Rats

    Get PDF
    The airway vagal preganglionic neurons (AVPNs) providing projections to intrinsic tracheobronchial ganglia are considered to be crucial to modulation of airway resistance in physiological and pathological states. AVPNs classified into inspiratory-activated AVPNs (IA-AVPNs) and inspiratory-inhibited AVPNs (II-AVPNs) are regulated by thyrotropin-releasing hormone (TRH)-containing terminals. TRH causes a direct excitatory current and attenuates the phasic inspiratory glycinergic inputs in II-AVPNs, however, whether and how TRH influences IA-AVPNs remains unknown. In current study, TRH regulation of IA-AVPNs and its mechanisms involved were investigated. Using retrogradely fluorescent labeling method and electrophysiology techniques to identify IA-AVPNs in brainstem slices with rhythmic inspiratory hypoglossal bursts recorded by a suction electrode, the modulation of TRH was observed with patch-clamp technique. The findings demonstrate that under voltage clamp configuration, TRH (100 nM) caused a slow excitatory inward current, augmented the excitatory synaptic inputs, progressively suppressed the inhibitory synaptic inputs and elicited a distinctive electrical oscillatory pattern (OP). Such a current and an OP was independent of presynaptic inputs. Carbenoxolone (100 μM), a widely used gap junction inhibitor, fully suppressed the OP with persistence of TRH-induced excitatory slow inward current and augment of the excitatory synaptic inputs. Both tetrodotoxin (1 μM) and riluzole (20 μM) functioned to block the majority of the slow excitatory inward current and prevent the OP, respectively. Under current clamp recording, TRH caused a slowly developing depolarization and continuously progressive oscillatory firing pattern sensitive to TTX. TRH increased the firing frequency in response to injection of a square-wave current. The results suggest that TRH excited IA-AVPNs via the following multiple mechanisms: (1) TRH enhances the excitatory and depresses the inhibitory inputs; (2) TRH induces an excitatory postsynaptic slow inward current; (3) TRH evokes a distinctive OP mediated by gap junction

    Optimized Live 4K Video Multicast

    Full text link
    4K videos are becoming increasingly popular. However, despite advances in wireless technology, streaming 4K videos over mmWave to multiple users is facing significant challenges arising from directional communication, unpredictable channel fluctuation and high bandwidth requirements. This paper develops a novel 4K layered video multicast system. We (i) develop a video quality model for layered video coding, (ii) optimize resource allocation, scheduling, and beamforming based on the channel conditions of different users, and (iii) put forward a streaming strategy that uses fountain code to avoid redundancy across multicast groups and a Leaky-Bucket-based congestion control. We realize an end-to-end system on commodity-off-the-shelf (COTS) WiGig devices. We demonstrate the effectiveness of our system with extensive testbed experiments and emulation

    Greedy Receivers in IEEE 802.11 Hotspots: Impacts and Detection

    Full text link
    • …
    corecore